Eliminating Analytical Laboratories  Biggest Bottlenecks


Why Should you Automate your Analytical Laboratory? 

While large parts of the process, such as sample handling, analysis, and data processing, can already be automated in analytical laboratories, the major bottlenecks, such as sample preparation and reagent/buffer preparation, often remain.

accroma is changing this and is the only manufacturer to offer standardized commercial-off-the-shelf automation solutions to analytical laboratories worldwide, finally bridging the gap between development and highly regulated GMP processes.

Reduced Costs

by saving commercial space and using resources smart.

Superior Accuracy and Precision

by minimizing human errors and -variability

Improved Efficiency

by full process automation, simplified method transfer while reducing cycle- and hands-on time.

Improved Compliance

by reducing deviations and getting traceable documentation.

Safer Workspace

Reduction of exposure to toxic substances and no glassware.



Bottleneck One – Sample Preparation

The foundation of every result is sample preparation.

No matter how good your analytical instruments are, the results are only as good as your sample preparation. accroTubes enable you to develop methods that are easy to automate, consume less solvent and prevent cross contamination.

accroShake

Entry-level device enabling you to develop automatable sample preparation methods. Seamless method transfer to the fully automated samplePrep system and ideal back-up device. And by the way, it is the only ball mill on the market that does not require cleaning. 

samplePrep

Sample in - Answer out. samplePrep allows you to fully automate, from a solid sample to result in standardized way.  This complete Lab in a Box not only shortens your development times in in early phases like formulation and accelerated  stability but also shortens batch release times while increasing documentation and traceability.  

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The accroTube – a Gamechanger

Each sample is prepared in its own disposable and closed tube which avoids evaporation, sample loss and carry over. This makes your workflows flexible, fast and reproducible.

Step 1

Sample Introduction

Introduce your sample and potential milling and / or mixing aids

Step 2

Grinding

Samples can be dry or wet milled by a very strong vertical shaking, like in a ball mill

Step 3

Liquid Handling

Solvents are introduced or transferred through the septum to perform solvent addition, pipetting, dilution, or phase separating steps

Step 4

Extraction

Extraction is performed with a very effective shaker or by ultra sonication

Step 5

Filtration

Sample solutions are automatically filtered directly into HPLC vial. Vials are capped and may be transferred directly into the analyser.

Note: this is just a very basic example workflow, you have no limit in terms of numbers of steps and you are free in the order of the individual steps – discuss your methods directly with us.

Applications

Bottleneck two – Eluent Preparation

bufferPrep

Preorder your aqueous buffers from anywher - quickly, traceable, and with full documentation. Integrated inventory and user management make traceability a breeze. Predictive models of platform recipes enable extra speed, while free-form recipes allow for full flexibility.

eluentPrep

bufferPrep, but one step further! Based on the existing platform, we have developed a method (patent pending) that allows you to add organic solvents. Your mobile phases for your HPLC – automatically prepared.  

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Introducing the accroma Way of Automation

Standardized System Hardware for easier scalability and simplified GMP qulification.

Flexible Software for simplified method development to deployment of validated workflows.

Unique, value-added consumables for reproducability and speed.

«Automation delivers more trustworthy results, improves traceability while increasing productivity and safety

A Synergistic Automation Portfolio 
Solutions for Sample & Buffer Preparation

To make HPLC analyses truly traceable, accroma has developed platforms that allow the key processes that influences HPLC results, such as sample preparation and the mobile phase preparation, to be automated in a simple, standardized, and therefore cost-efficient manner.

Sample Volume

The accroTube technology makes the accroma system suitable even for laboratories with low and diverse sample volumes. We automate your sample preparation without sacrificing flexibility.

Method Transfer is Simple

The automation of manual sample preparation method may not require any adjustments. If a method needs to be modified for automation, there is a simple and defined process to proof equivalence.

Your Tubes are Sustainable

To ensure scientific accuracy and reproducibility, accroma requires material of highest quality and inertness. Sustainability is important to us for which reason we use recyclable materials like polyethylene and iron. Both materials are 100% recyclable and can be reused as secondary raw materials. However, we need your help to separate content, tubes and steel balls.

Large sample type compatibility

The volume range of the accroTubes and the functionalities of the system allow to automate the sample preparation of a wide range of sample types. Therefore, it is used in numerous industries for the preparation of samples for chemical analysis. Whether it is the determination of Active Pharmaceutical Ingredients in tablets or contaminants in food, we offer sample IN – Answer OUT automation.

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